She was the mother of Odysseus by Laërtes. In Book XI of the Odyssey, Odysseus makes a trip to the underworld to seek the advice of the dead prophet Tiresias. In the underworld, he encounters many spirits, including that of his mother, Anticlea. Initially, he rebuffs her since he is waiting for the prophet to approach.
After speaking with Tiresias, however, Odysseus allows his mother to come near and lets her speak. She asks him why he is in the underworld while alive, and he tells her about his various troubles and failed attempts to get home. Then he asks her how she died and inquires about his family at home. She tells him that she died of grief, longing for him while he was at war. Anticlea also says that Laërtes "grieves continually" for Odysseus. Anticlea further describes the condition of Odysseus' wife Penelope and son Telemachus.